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Wednesday, February 21, 2018

Google - Algoritimos

Google actualiza algoritmos para “enterrar” páginas de baixa qualidade

logo googleGoogle acabou recentemente de modificar os seus algoritmos qua classificam as páginas de baixa e alta qualidade no seu motor de busca. A gigante das buscas está sempre a fazer alterações no seu motor de busca, mas sem muita publicidade e na maioria das vezes essas alterações passam despercebidas pelo público. No entanto, esta última atualização afecta cerca de 11,2% de todas as pesquisas, pelo que a empresa achou importante informar todos.
A Google lançou uma atualização que reduz a contagem das páginas de baixa qualidade e aumenta a classificação para as páginas de boa qualidade. A empresa define as páginas de baixa qualidade aquelas que copiam conteúdo de outras páginas que simplesmente "não são muito úteis". No entanto, a empresa reconhece que sites de alta qualidade são aqueles que produzem conteúdo original e de informação que incluam pesquisa, análise e outro conteúdo original.
"A Google depende do conteúdo de alta qualidade criado por maravilhosas páginas de todo o mundo, e nós temos a responsabilidade de incentivar um ecossistema web saudável. Por isso, é importante que as páginas de alta qualidade sejam recompensadas, e é exatamente isso que essa mudança faz"./.../

Parkinson's Disease


Flushing out 'zombie cells' could help stave off Parkinson's, study suggests

Possible approach to treating effects of neurodegenerative diseases – and even ageing – revealed by trial
Senescent cells lose a specific protein from their nuclei, indicated by the green colour above. This protein is lost from astrocytes (red cells), but not from neighbouring cells.
 Senescent cells lose a specific protein from their nuclei, indicated by the green colour above. This protein is lost from astrocytes (red cells), but not from neighbouring cells. Photograph: Georgia Woods, PhD Buck Institute for Research on Aging
In work that could open a new front in the war on Parkinson’s disease, and even ageing itself, scientists have shown that they can stave off some of the effects of the neurodegenerative disease by flushing “zombie cells” from the brain.
The research in mice raises hopes for a fresh approach to treating the most common forms of Parkinson’s disease, which typically arise through a complex interplay of genetics, lifestyle and potentially toxic substances in the environment.
But the approach may have benefits far beyond Parkinson’s, with other neurodegenerative diseases – and the ageing process more broadly – all being linked to the ill effects of these “senescent” cells, which linger in tissues after entering a state of suspended animation in the body./.../
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Study suggests that exenatide, currently used to treat type 2 diabetes, improves movement-related issues and might also slow the progression of the disease
A drug commonly used to treat diabetes could help those living with Parkinson’s disease, research has revealed.
By 2020 it is predicted that 162,000 individuals in the UK will be living with the condition. While existing drugs help to control its symptoms, there are currently none available which slow or halt its progression.
But now scientists say they have found that a drug commonly used to treat type 2 diabetes appears to improve movement-related issues. 
The benefit persisted even when the drug had not been taken for 12 weeks, suggesting it might be helping to slow the progression of the disease./.../

Raymond John Lipicky, M.D. ( +2018)


Raymond J Lipicky

A Tribute to Dr. Ray Lipicky: The Man Who Transformed Cardiology

Milton Packer, Robert Califf, Norman Stockbridge and Robert Fenichel pay tribute

  • by 
Most cardiologists assume that the way we currently think about things in cardiology has always been part of our DNA. We are strongly evidence-based, and we are skeptical of mechanisms that have no supporting data. We recognize the limitation of small trials, and we understand how missing data creates bias. We know that rigorous clinical trials are the only way to inform our use of drugs.
Has cardiology always been this way? Actually, no.
Forty years ago, thinking in cardiology was dominated by wonderful story-telling, but without much evidence. Trials were small, and many were not well designed or executed. They often focused on things that we thought were important, based on our beliefs about a disease. We knew that shortcuts commonly gave the wrong answer, but we embraced them because we did not know better.
One man made all the difference: Dr. Raymond Lipicky.
Ray led the FDA Division of Cardiac and Renal Drug Products from 1981-2002. During those 21 years, his unique intellect and way of thinking transformed the cardiovascular drug evaluation and approval process. Too slowly, his approach to cardiovascular drugs is now being adopted in other therapeutic areas./.../

Tuesday, February 20, 2018

Internet Preditiva

Google investe em uma tal de Internet Preditiva

Saiba qual é a proposta e como ela deve impactar os negócios digitais de muitas empresas

Mike Elgan, Computerworld / EUA

Publicada em 20 de fevereiro de 2018 às 07h37

O Google quer que você continue usando o Google. Então para te manter interessado, a gigante está trabalhando duro para aplicar algumas das tecnologias mais avançadas do mundo para tornar as suas atividades on-line mais rápidas e fáceis.
A empresa está atacando em diversas frentes. Uma delas é a chamada predição. Basicamente, o Google está tentando descobrir como adivinhar o que você vai querer fazer, para então tornar essa predição disponível como uma opção instantânea. 
Esse poder de previsão vai transformar como os funcionários e os executivos em empresas e em outros negócios irão trabalhar. A Internet preditiva fará pelo trabalho o que os carros autônomos farão pelo transporte.
Tudo começa com uma mensagem.

Monday, February 19, 2018

Injustice

How the Brain Responds to Injustice

by Neuroscience News
A new study implicates oxytocin in corrective punishment that helps maintain fairness.
Neuroscience News | February 19, 2018 at 1:35 pm | Tags: alcoholjustice | URL: https://wp.me/p4sXNK-cbA
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Calcium and Parkinson's D


Calcium May Play a Role in the Development of Parkinson’s

by Neuroscience News
A new Nature Communications study reveals increased calcium levels in brain cells may play a significant role in the development of Parkinson's disease.
Neuroscience News | February 19, 2018 at 9:47 am | Tags: alpha-synucleindSTORMSUVs | URL: https://wp.me/p4sXNK-cbj
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Billions Computers

Your Cortex Contains 17 Billion Computers

Neural networks of neural networks

Credit: brentsview under CC BY-NC 2.0
Brains receive input from the outside world, their neurons do
 something to that input, and create an output. That output
may be a thought (I want curry for dinner); it may be an action
(make curry); it may be a change in mood (yay curry!).
Whatever the output, that “something” is a transformation of
some form of input (a menu) to output (“chicken dansak, please”).
And if we think of a brain as a device that transforms inputs to
outputs then, inexorably, the computer becomes our analogy of
choice.

Brainwaves Music

Brainwaves Show How Exercising to Music Bends Your Mind

by Neuroscience News
Listening to music while exercising reduces focus, but boosts energy levels and enjoyment, researchers report.
Neuroscience News | February 19, 2018 at 6:45 am | Tags: Brunel Universitypodcasts | URL: https://wp.me/p4sXNK-cb8
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European Society of Cardiology Epidemiologic Atlas





Epidemiology of cardiovascular disease: the new ESC Atlas and beyond 

European Heart Journal, Volume 39, Issue 7, 14 February 2018, Pages 489–492,https://doi.org/10.1093/eurheartj/ehy070
Published:
 
14 February 2018
graphic
For the podcast associated with this article, please visit https://academic.oup.com/eurheartj/pages/Podcasts.
The prevalence and incidence of cardiovascular disease are known to vary among different countries,1 most probably depending on income, culture, and healthcare systems, but precise data have been lacking so far. The novel ‘European Society of Cardiology: Cardiovascular Disease Statistics 20172 by the Atlas Writing Group compiled cardiovascular disease statistics of the 56 ESC member countries and compared high-income and middle-income ESC member states.