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Wednesday, November 26, 2008

Periodontal disease associated with elevated levels of Lp-PLA2

Periodontal disease associated with elevated levels of Lp-PLA2
NOVEMBER 25, 2008 | Michael O'Riordan

New York, NY - Individuals with a history of periodontal disease also have increased levels of systemic inflammation, according to the results of a new study [1]. Investigators observed a significant association among those with periodontal disease and elevated levels of the inflammatory marker lipoprotein-associated phospholipase A2 (Lp-PLA2).

"To our knowledge, this is the first report of an association between oral health and Lp-PLA2," write lead author Heidi Mochari (Columbia University Medical Center, New York) and colleagues in the December 1, 2008 issue of the American Journal of Cardiology. "These data support a possible independent association between oral health and inflammation, suggesting that inflammation may be a factor in the relation between oral health and cardiovascular disease."/.../

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