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Thursday, August 05, 2010

Gene Variants Linked to Lipid Levels

New Gene Variants Linked to Lipid Levels

By Michael Smith, North American Correspondent, MedPage Today
Published: August 04, 2010
Reviewed by Dori F. Zaleznik, MD; Associate Clinical Professor of Medicine, Harvard Medical School, Boston and
Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner

In a genetic analysis of more than 100,000 people of European ancestry, researchers have found 95 common genetic variants -- 59 of them previously unknown -- that influence lipid levels by regulating nearby genes.

Some of the variants are clustered near genes already known to be involved in regulating lipid levels but "scores" are near genes not previously linked to lipoprotein metabolism, the researchers wrote in two papers in the Aug. 5 issue of Nature.

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