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Wednesday, May 18, 2016

Depression

How Depression and Antidepressant Drugs Work


Summary: A new study shows the effectiveness of ketamine in treating depression in a mouse model of the disease and also helps bring together two hypotheses for the cause of depression.
Source: Penn State University.
New insight from depressed mice helps researchers unite two hypotheses.
New research demonstrates the effectiveness of ketamine to treat depression in a mouse model of the disease and brings together two hypotheses for the cause of depression. The research, led by Bernhard Lüscher, professor of biology and of biochemistry and molecular biology at Penn State University, is in press and will be published in the September 15, 2016, print edition of the journalBiological Psychiatry.

“Depression is the second most expensive health problem that we face worldwide, but this fact is not very well known because there is a stigma attached to depression and people don’t like to talk about it,” said Lüscher. “About 17 percent of Americans will be treated for depression at some point in their lives, but there are limited treatment options and about one-third of patients do not respond to these treatments.”/.../

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