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Sunday, December 25, 2016

"granulocyte-macrophage colony stimulating factor” (GM-CSF)

Method discovered to remove damaging amyloid plaques found in Alzheimer’s disease

December 23, 2016
Illustration of formation of beta-amyloid plaques. Enzymes act on the APP (amyloid precursor protein) and cut it into fragments. The beta-amyloid fragment is crucial in the formation of senile plaques in Alzheimer’s disease. (credit: National Institute on Aging/NIH)
German scientists have discovered a strategy for removing amyloid plaques — newly forming clumps in a brain with Alzheimer’s disease that are created by misfolded proteins that clump together and damage nerve cells.
The scientists from the German Center for Neurodegenerative Diseases (DZNE) in Munich and the Ludwig Maximilians University (LMU) Munich took aged microglia cells (the  scavenger cells of the brain’s… read more

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