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Wednesday, July 12, 2017

AD and Immune cells

Missing Link Discovered Between Immune Cells and Alzheimer’s Disease

Source: Cornell University
By studying the effects of immune cells that surround blood vessels in the brain, Weill Cornell Medicine researchers have discovered a new pathway involving these cells that may contribute to the cause of Alzheimer’s disease.
Image shows immune cells and blood vessels in the brain.
Immune cells called perivascular macrophages (green) are observed in close contact with blood vessels in the brain (red). When activated by plaque deposits from the peptide amyloid-beta, a hallmark of Alzheimer’s disease, perivascular macrophages produce damaging free radicals that paralyze blood vessels and deprive the brain of the needed supply of nutrients and oxygen. NeuroscienceNews.com image is credited to the researchers.

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